Dexamethasone and Etoricoxib for Pain Prevention Following Periodontal Surgery

O Uso de Dexametasona e Etoricoxibe Para a prevenção e Controle da Dor pós-operatória após Cirurgia Periodontal

Status

Completed

Phases

Phase 2Phase 3

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00970112

Enrollment

Registered

2009-09-02

Start date

2008-11-30

Completion date

2010-03-31

Last updated

2010-05-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pain Control

Keywords

pain, pain assessment

Brief summary

The purpose of this study is to investigate whether preemptive medication with dexamethasone or etoricoxib provides better pain management and control than placebo following periodontal surgery.

Interventions

PROCEDUREOpen Flap Debridement

Open flap debridement - access flap + scaling and root planning

Study design

Allocation

RANDOMIZED

Intervention model

CROSSOVER

Primary purpose

TREATMENT

Masking

QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

20 Years to 55 Years

Healthy volunteers

Yes

Inclusion criteria

* Patients presenting moderate or severe periodontitis after nonsurgical periodontal treatment with clinical signs of inflammation

Exclusion criteria

* Pregnant * Diabetes mellitus * Heart diseases * Allergic to components of the medications * Risk of endocarditis

Design outcomes

Primary

Measure	Time frame	Description
pain	up to 3 days	hourly for the 8 first hours after surgery 3 times a day on the following 3 days

Countries

Brazil

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026