Pulmonary Disease, Chronic Obstructive
Conditions
Keywords
weaning, adaptive support ventilation, COPD
Brief summary
Adaptive support ventilation (ASV) is a closed loop ventilation mode that can act both as pressure support (PSV) and pressure controlled (PCV) ventilation. Weaning with ASV shows promising results mainly in post-cardiac surgery patients. The aim of this randomized controlled study was to test the hypothesis that weaning with ASV could reduce the weaning duration in patients with chronic obstructive pulmonary disease (COPD) when compared with PSV.
Interventions
PROCEDUREComparison of two different modes for weaning from mechanical ventilation
Chronic obstructive pulmonary disease patients under mechanical ventilation were randomized to adaptive or pressure support ventilation modes when they met the weaning criteria.
Sponsors
Izmir Dr Suat Seren Chest Diseases and Surgery Education and Research Hospital
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
SCREENING
Masking
SINGLE (Subject)
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Diagnosis of COPD * On invasive mechanical ventilation for at least 24 hours because of hypoxemic and/or hypercapnic respiratory failure
Exclusion criteria
* Mechanical ventilation less then 24 hours (self extubation or death), * Having a tracheotomy and * COPD coexisted with severe cardiac or neurologic diseases.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Weaning duration | — |
Secondary
| Measure | Time frame |
|---|---|
| Weaning success | — |
| Length of stay in the ICU | — |
Countries
Turkey (Türkiye)
Outcome results
None listed