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Hemodynamic Changes in Off-pump Coronary Artery Bypass Grafting

Hemodynamic Changes in Off-pump Coronary Artery Bypass Grafting

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT00967278
Enrollment
Unknown
Registered
2009-08-27
Start date
Unknown
Completion date
Unknown
Last updated
2009-09-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Coronary Artery Disease

Keywords

OPCAB, pulmonary artery catheter, esophageal doppler, hemodynamics

Brief summary

The purpose of this study is to study the positioning and stabilization of different cardiac walls performed during off-pump coronary artery bypass grafting (CABG) may have dissimilar impact on hemodynamics. The objective is to evaluate hemodynamics during distal coronary anastomoses in different cardiac walls.

Detailed description

* Twenty patients undergoing off-pump CABG monitored with pulmonary artery catheter and esophageal doppler will be enrolled. * Patients with a left ventricular ejection fraction \<50%, age \>80 yr, creatinine \>1.4 mg/dl, reoperation, valvular heart disease or chronic obstructive pulmonary disease were excluded * Data will be collected after volemic and hemodynamic adjustments, after heart positioning and establishment of a suction stabilizer and before its removal in anterior, lateral or posterior wall artery anastomosis. * Data was compared by means of two-way repeated measures ANOVA.

Interventions

None listed

Sponsors

University of Sao Paulo
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
CROSS_SECTIONAL

Eligibility

Sex/Gender
ALL
Age
No minimum to 80 Years
Healthy volunteers
No

Inclusion criteria

* Normal left ventricular function * Minimal to moderate surgical risk according to criteria proposed by Higgins et al. (JAMA. 1992 May 6;267(17):2344-8)

Exclusion criteria

* Patients with a left ventricular ejection fraction \<50%, * Age \>80 yr * Creatinine \>1.4 mg/dl * Reoperation * Valvular heart disease * Chronic obstructive pulmonary disease * High surgical risk according to criteria proposed by Higgins et al. (JAMA. 1992 May 6;267(17):2344-8)

Countries

Brazil

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026