Ghrelin, Growth Hormone and Growth Factors at High Altitude

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT00966134

Enrollment

Unknown

Registered

2009-08-26

Start date

2002-04-30

Completion date

2005-09-30

Last updated

2010-02-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Growth Hormone, Healthy

Keywords

mountain medicine, ghrelin, growth hormone, hypoxia, physiology of hormonal adaptation to high altitude

Brief summary

Regulation of ghrelin, growth hormone and growth factors at high altitude and their change during ascent to high altitude has not been studied in depth yet. The study includes 33 volunteers (12f) investigated at sea level, 4 days after ascent to 3440m and 14 days after ascent to 5400-5900m. The investigators hypothesized that during ascent growth hormone levels would increase to compensate for the higher energy needs at high altitude.

Interventions

OTHERexposure to high altitude

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to 65 Years

Healthy volunteers

Yes

Inclusion criteria

* Healthy and good physical fitness

Design outcomes

Primary

Measure	Time frame
Ghrelin, growth hormone, insulin-like growth factor I (IGF-I), IGF binding protein 1 (IGFBP1), IGF binding protein 2 (IGFBP2), IGF binding protein 3 (IGFBP3), acid-labile subunit (ALS), insulin, prolactin	14 days

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026