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Treadmill Training With Additional Body Load: Effects on Gait of Subjects With Parkinson´s Disease

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT00964652
Enrollment
9
Registered
2009-08-25
Start date
2007-08-31
Completion date
2008-12-31
Last updated
2009-08-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Parkinson´s Disease

Keywords

treadmill, body load, Parkinson's disease, gait

Brief summary

Background: Studies about the effects of walking training with additional body load in Parkinson's disease (PD) are lacking. There is evidence that the increase of body load during treadmill walking improves reflex activity and leg extensor muscle activity, which are impaired in subjects with PD. Purpose: The purpose of this study was to assess the effects of treadmill walking training with additional body load on the ground reaction forces, spatiotemporal, and kinematic variables of the gait of subjects with moderate PD. Design: This study was an A1-B-A2 single-case. Setting: The evaluation and the training were conducted in a movement analysis laboratory, and at the rehabilitation unit of the University, respectively. Participants: Nine patients with PD (Hoehn and Yahr 2 through 3) and gait disturbances. Interventions: Phases A1 and A2 included 6 weeks of gait training on a treadmill with 10% increase of normal body mass. Phase B included 6 weeks of conventional physical therapy. Measurements: Measures included the ground reaction forces, spatiotemporal, and kinematic variables during overground walking, at baseline and after each phase.

Interventions

The training program was divided into three phases (A1-B-A2): treadmill training with additional body load (A1), control condition (conventional physical therapy) (B). and treadmill training with additional body load again (A2). Each phase lasted six weeks, totaling 18 weeks. Both evaluations and training were performed during on-phase of the medication cycle.

Sponsors

Universidade Federal de Sao Carlos
Lead SponsorOTHER

Study design

Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
51 Years to 81 Years
Healthy volunteers
No

Inclusion criteria

* Idiopathic PD (previously diagnosed by one specialist physician,) * Hoehn and Yahr (H-Y) stages 2 through 3, * Absence of dementia (Mini-Mental Status Examination - MMSE, defined according to educational level) and, * Capacity to ambulate independently for at least 10 meters.

Exclusion criteria

* Change medication (dopaminergic) during the study period, * Use treadmill for at least six months prior to the study, and * Other neurologic problems or musculoskeletal, cardiovascular and respiratory disease or uncorrected visual deficit that could represent risk and interfere in the performance of the training.

Design outcomes

Primary

MeasureTime frame
Significant increase in propulsive forces, stride length, speed, maximum hip extension during stance were observed after the training program.4 times, once before treatment, and 3 after each treatment phase.

Countries

Brazil

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026