Computed Tomographic (CT) Perfusion and CT Angiography as Screening Tools for Vasospasm Following Subarachnoid Hemorrhage

Computed Tomographic Perfusion and Computed Tomographic Angiography as Screening Tools for Vasospasm Following Subarachnoid Hemorrhage

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT00962546

Enrollment

Registered

2009-08-20

Start date

2009-09-30

Completion date

2011-12-31

Last updated

2014-12-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cerebral Aneurysm, Cerebral Vasospasm, Subarachnoid Hemorrhage

Keywords

cerebral aneurysm, subarachnoid hemorrhage, cerebral vasospasm, computed tomographic perfusion, computed tomographic angiography

Brief summary

Cerebral vasospasm is a devastating complication of subarachnoid hemorrhage after cerebral aneurysm rupture leading to cerebral ischemia and potentially cerebral infarction. The current gold standard diagnostic imaging study for cerebral vasospasm is catheter cerebral angiography, an invasive diagnostic procedure carrying a complication rate of 1-2% per procedure. Computed tomographic perfusion imaging (CTP) and computed tomographic angiography (CTA) are noninvasive diagnostic imaging studies frequently utilized in the evaluation of embolic and thrombotic cerebral infarct. The investigators hypothesize that CTP and CTA may be utilized as screening tools for cerebral vasospasm following aneurysmal subarachnoid hemorrhage requiring treatment and provide prognostic information.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* subarachnoid hemorrhage after aneurysm rupture

Exclusion criteria

* renal insufficiency * pregnancy * contrast reaction

Design outcomes

Primary

Measure	Time frame
CT perfusion parameters	at time of catheter angiogram

Secondary

Measure	Time frame
Disposition at discharge	At time of hospital discharge
vessel narrowing by CT angiography	at time of catheter angiogram

Countries

United States

Outcome results