Motor Development and Orthoses in Spinal Muscular Atrophy (SMA)

Assessment of Motor Development Related to Use of Orthoses in SMA II and III

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT00961103

Enrollment

Registered

2009-08-18

Start date

2009-10-12

Completion date

2011-04-04

Last updated

2025-12-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Spinal Muscular Atrophy

Keywords

spinal muscular atrophy, motor development, orthoses

Brief summary

Spinal Muscular Atrophy (SMA) is neurodegenerative disease of anterior horn cells of spinal cord and represents the second more frequent pathology in childhood. According to the age of onset and the maximum motor function the disorder is classified in 4 types. Patients with SMA II and SMA III often use orthoses to achieve postural and dynamic functions. In this retrospective observational study the investigators describe the characteristics of sitting position, standing and walking correlated to type and time of orthoses used.

Detailed description

We collect data from patients with SMA II and SMA III referred to UDGEE from jan. 1995 to dec. 2008. We estimate to achieve informations about 50-70 patients.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Healthy volunteers

Inclusion criteria

* Clinical and genetics diagnosis of SMA II and SMA III

Exclusion criteria

* N/A

Design outcomes

Primary

Measure	Time frame
time and percentage of sitting, standing, walking achievement in SMA II and SMA III	aug.2009- nov.2009

Secondary

Measure	Time frame
characteristics and percentage of orthoses for postural sitting control , standing and walking in SMA II and SMA III	aug. 2009 - dec.2009

Countries

Italy

Outcome results