Vitamin D, Blood Pressure, Lipids, Infection and Depression

Status

Completed

Phases

Phase 3

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00960232

Enrollment

250

Registered

2009-08-17

Start date

2009-09-30

Completion date

2010-12-31

Last updated

2012-09-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hypovitaminosis D

Keywords

vitamin D, blood pressure, lipids, infection, depression

Brief summary

There are numerous indications for a relation between low serum levels of 25(OH)D and blood pressure, lipid levels, frequency of infections and tendency towards depression. Whether it is a causal relationship it is not known, and can best be studied with a vitamin D intervention. The investigators hypothesis is that supplementation with a high dose vitamin D (40.000 IU per week) will have a beneficial effect on these parameters.

Interventions

DRUGCholecalciferol

40.000 IU cholecalciferol per week for 6 months

DRUGplacebo

placebo

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

30 Years to 75 Years

Healthy volunteers

Yes

Inclusion criteria

* men and women 30 - 75 years of age * low serum 25(OH)D levels

Exclusion criteria

* diabetes * other serious diseases * hypercalcemia

Design outcomes

Primary

Measure	Time frame
Depression score	6 months
Blood pressure	6 months
Lipid profile	6 months
Frequency of infections	6 months

Countries

Norway

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Mar 26, 2026