Breast Cancer
Conditions
Keywords
recurrent breast cancer, stage IA breast cancer, stage IB breast cancer, stage II breast cancer, stage IIIA breast cancer, stage IIIB breast cancer, stage IIIC breast cancer, stage IV breast cancer
Brief summary
RATIONALE: Studying the genes expressed in samples of blood from patients with cancer may help doctors identify biomarkers related to cancer. It may also help doctors predict how patients will respond to chemotherapy. PURPOSE: This clinical trial is studying blood samples in patients with breast cancer.
Detailed description
OBJECTIVES: * Identify constitutional gene variants associated with a change in response. OUTLINE: Blood samples are collected periodically for analysis of genetic factors.
Interventions
OTHERlaboratory biomarker analysis
Sponsors
Centre Oscar Lambret
Eligibility
Sex/Gender
FEMALE
Age
18 Years to 120 Years
Healthy volunteers
No
Inclusion criteria
DISEASE CHARACTERISTICS: * Histologically confirmed breast carcinoma * Received first-line chemotherapy (in neoadjuvant or metastatic setting) comprising anthracyclines and/or taxanes, including for a second primary cancer * Patient agrees to conservative surgery * Hormone receptor status not specified PATIENT CHARACTERISTICS: * Menopausal status not specified * No contraindication for chemotherapy comprising anthracyclines and/or taxanes PRIOR CONCURRENT THERAPY: * See Disease Characteristics * No prior adjuvant therapy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Histologic complete response (Chevallier and Sataloff) or tumor response (RECIST) | — |
Countries
France
Contacts
PRINCIPAL_INVESTIGATORJacques Bonneterre, MD, PhD
Centre Oscar Lambret
Outcome results
None listed