Brazilian Intervention to Increase Evidence Usage in Practice - Acute Coronary Syndromes

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00958958

Acronym

BRIDGE

Enrollment

1150

Registered

2009-08-14

Start date

2010-01-31

Completion date

2012-02-29

Last updated

2012-02-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute Coronary Syndrome

Keywords

Acute Coronary Syndrome, randomized cluster trial, quality improvement

Brief summary

Phase 1: An observational study (registry) will be conducted which will objectively document the ACS clinical practice in Brazilian public hospitals, and identify the important barriers for the evidence usage incorporation in the clinical practice. Phase 2: A Cluster randomized clinical trial in which public hospital will be randomized to receive or not a multifaceted strategy in order to increase evidence based therapy in clinical practice.

Detailed description

STUDY POPULATION: Patients with thoracic pain who the emergency department physician suspects of ACS and plans start a treatment for this issue; It will be excluded patients transferred of others institutions with 12 hours of symptoms. PROGRAM: There are multifaceted Interventions Including 1. Distribution of educational materials 2. Case manager: Use of a trained person who works in the hospital and will be responsible to assure that all interventions were used 3. Reminders: specific information that is designed or intended to prompt a health professional to recall information (patient bracelets, labels, posters, pocket cards, checklists). 4. Practical training ENDPOINTS: Phase 1 Primary outcome; patient who've received interventions based on evidence proportion informed by the indicators; Phase 2 Primary outcome: Increase of prescription of evidence based treatment in clinical practice Secondary outcome Total mortality and major cardiovascular events

Interventions

OTHERmultifaceted strategy

There are multifaceted Interventions Including 1. Distribution of educational materials: distribution of published or printed recommendations for clinical care. 2. Case manager: Use of a trained person who works in the hospital and will be responsible to assure that all interventions were used 3. Reminders 4. Practical training

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Masking

SINGLE (Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

Patient Eligibility criteria Inclusion Criteria: * Patients with thoracic pain who the emergency department physician suspects of ACS and plans start a treatment for this issue

Exclusion criteria

* Patients transferred from others institutions within 12 hours of the symptoms Cluster Eligibility Criteria * National Public Hospitals with emergency department. A cluster can be one hospital with emergency department, or 2 or more hospitals (for example: 1 emergency hospital and 1 general hospital which receive the patients to perform PCI).

Design outcomes

Primary

Measure	Time frame
Phase 1: patient who've received interventions based on evidence proportion informed by the indicators	9 months
Phase 2: increase of prescription of evidence based treatment in clinical practice	6 months

Secondary

Measure	Time frame
Total mortality and major cardiovascular events	6 months

Countries

Brazil

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Mar 26, 2026