Cystitis
Conditions
Keywords
ketamine, bladder dysfunction, bladder mucosa, mechanisms
Brief summary
This study is aimed to evaluate the relationship between ketamine abused and bladder dysfunction and its possible mechanisms.
Interventions
OTHERketamine
Sponsors
Taipei Medical University WanFang Hospital
Study design
Observational model
CASE_ONLY
Time perspective
CROSS_SECTIONAL
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* Adult male or female * Cystitis (the clinicians ruled out the causes of bacterial infection) * Frequent micturition * The clinicians are willing to sign the ICF
Exclusion criteria
* Suffers from the urinary system disease, is not suitable to carry on the urinary bladder biopsy sampling * Suffers from other diseases, doctor recognized that is not suitable to carry on the sampling * The clinicians are not willing to sign the ICF
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Substance Abuse Situation Record | 1 day | Substance abuse situation record: ketamine |
Secondary
| Measure | Time frame |
|---|---|
| Urinary Bladder Capacity | 1 day |
Countries
Taiwan
Participant flow
Participants by arm
| Arm | Count |
|---|---|
| Case ketamine + Cystitis
ketamine | 44 |
| Total | 44 |
Baseline characteristics
| Characteristic | Case |
|---|---|
| Age, Categorical <=18 years | 0 Participants |
| Age, Categorical >=65 years | 0 Participants |
| Age, Categorical Between 18 and 65 years | 44 Participants |
| Age, Continuous | 28 years STANDARD_DEVIATION 6 |
| Region of Enrollment Taiwan | 44 participants |
| Sex: Female, Male Female | 17 Participants |
| Sex: Female, Male Male | 27 Participants |
Adverse events
| Event type | EG000 affected / at risk |
|---|---|
| deaths Total, all-cause mortality | — / — |
| other Total, other adverse events | 0 / 44 |
| serious Total, serious adverse events | 0 / 44 |
Outcome results
Primary
Substance Abuse Situation Record
Substance abuse situation record: ketamine
Time frame: 1 day
| Arm | Measure | Value (MEAN) |
|---|---|---|
| Case | Substance Abuse Situation Record | 2 years |
Secondary
Urinary Bladder Capacity
Time frame: 1 day