Obstructive Sleep Apnea
Conditions
Keywords
obstructive sleep apnea, exercise training, aerobic exercise, resistance exercise
Brief summary
The purpose of this study is to compare the efficacy of two different physical activity regimens as complementary or alternative treatment options for the treatment of obstructive sleep apnea. A secondary purpose of the study is to examine the effects of these activity regimens on various health consequences of obstructive sleep apnea, including blood pressure, systemic inflammation, and daytime functioning.
Interventions
Individuals will complete four days of aerobic exercise of moderate intensity (60% of maximal VO2, approximated from heart rate). Duration of aerobic activity will gradually increase from weeks 1 through 4 until 180 min of aerobic exercise at the prescribed intensity is performed each week. Following aerobic exercise on two days per week, moderate-intensity resistance training will be performed using eight different resistance machines. One set of 8-12 repetitions will be performed during weeks 1-4; from week 5-on, 2 sets of 8-12 repetitions will be performed.
Individuals will perform supervised whole-body flexibility exercises on two days per week. Two sets of each exercise will be performed, with the duration of each stretch gradually increasing from 15 sec to 30 sec. A total of 15-20 stretches, focusing on whole-body flexibility, will be performed.
Sponsors
Study design
Eligibility
Inclusion criteria
* moderate-intensity obstructive sleep apnea (AHI \>= 15) * sedentary status
Exclusion criteria
* current treatment for obstructive sleep apnea (CPAP, oral devices, etc.) * significant cardiovascular, pulmonary, or metabolic disease * uncontrolled hypertension * inability to exercise (e.g., musculoskeletal, neuromuscular, orthopedic problems)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Laboratory polysomnographic assessment of apnea-hypopnea index | pre- and post-intervention (12 weeks later) |
Countries
United States