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Prevention of Perioperative Acute Renal Failure

Prevention of Perioperative Acute Renal Failure in Abdominal Surgery

Status
Terminated
Phases
Phase 4
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT00953940
Enrollment
600
Registered
2009-08-06
Start date
2005-06-30
Completion date
2011-05-31
Last updated
2011-07-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Abdominal Surgery

Brief summary

The purpose of this study is to measure the acute renal dysfunction on the first, second, seventh and twentieth days.

Interventions

DRUGIsotonic saline

Isotonic saline administrated i.v at 1.5 ml/Kg/h , 8 to 12 h before surgery

Sponsors

Fondo de Investigacion Sanitaria
CollaboratorOTHER
Hospital Universitario Ramon y Cajal
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* All patients who are undergoing elective abdominal surgery after appropriate information of the study, and its possible risks that may arise therefrom and that at any time to refuse their cooperation, give a written consent to participate in the study. * Patients who at the time of the interview have an ASA between 2 and 4. * Patients with chronic kidney failure mild moderate (serum creatinine between 1.5 and 3.0 mg / dl) can be included.

Exclusion criteria

* Chronic kidney diseases with serum creatinine higher than 3.0 mg /DL * Laparoscopic abdominal surgery * ASA 1 and ASA 5 patients. * Patients with cardiac insufficiency, ascites and respiratory insufficiency * Diastolic hypertension \> 100 mmHg

Design outcomes

Primary

MeasureTime frame
Serum creatinine in the first, second, seventh and twenty after surgery in patients undergoing elective abdominal surgery.5 years

Countries

Spain

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Mar 2, 2026