Infertility
Conditions
Keywords
endometrium, histology, pregnancy
Brief summary
The purpose of this study is to investigate any potential advantages of replacing human chorionic gonadotropin (uhCG) with recombinant human chorionic gonadotropin (recHCG) for final oocyte maturation with regard to Ovarian hyperstimulation syndrome (OHSS)pathophysiology, endometrium receptivity and embryo quality and clinical pregnancy.
Detailed description
Biopsies of endometrium were taken in different groups Pregnancy rates were compared among defferent groups
Interventions
bolus 10000 units for ovulation triggering
bolus 250 mcg for ovulation triggering in IVF patients
Sponsors
Merck Serono International SA
Universitair Ziekenhuis Brussel
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Investigator)
Eligibility
Sex/Gender
FEMALE
Age
20 Years to 36 Years
Healthy volunteers
No
Inclusion criteria
* Less than 36 years old * Male or tubal infertility * FSH\<12 on day 3
Exclusion criteria
* Endometriosis stage 3 & 4
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| endometrium histology on the day of OPU | day of oocytre pick up |
Secondary
| Measure | Time frame |
|---|---|
| pregnancy rate | 14 days after oocyte pick up |
Countries
Belgium
Outcome results
None listed