Carpal Tunnel Syndrome, Multiple Excitability Test
Conditions
Keywords
Carpal Tunnel Syndrome, Multiple Excitability Test, Nerve Conduction Study, QtracW, carbamazepine, Acupuncture
Brief summary
The goal of the study is to utilize BCTQ(Boston Carpal Tunnel Questionnaire), VAS (Visual Analog Scale), NCS (Nerve Conduction Study), and MET(Multiple Excitability Test) to evaluate and compare the efficacy of Acupuncture Therapy and Carbamazepine in Patients with Carpal Tunnel Syndrome.
Interventions
DRUGCarbamazepine
Carbamazepine 200mg, 1/2 tablet, TID for 1 month
PROCEDUREAcupuncture
Acupuncture
Sponsors
Taipei Medical University WanFang Hospital
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
20 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Age greater than 20 years old * outpatient or inpatient subject with numbness of arm, clinically met diagnostic criteria of AAEM(American association of Electrodiagnostic Medicine CTS task force), and proven to have distal motor neurological disorder through nerve Conduction Study (distal motor latency \>4.6 msec, decreased SNAP \< 12uV or prolonged median sensory distal latency (palm to wrist) \> 2.5msec)。 * Willing to sign the Informed Consent form
Exclusion criteria
* subject with external hand injury or disformation * subject with Polyneuritis or Cervical nerve root lesions * Subject with peripheral hypertrophy, hypothyroidism, multiple myeloma, or amyloidosis * Allergic to Carbamazepine or similar type of medicine * inability to act independently, or in the opinion of the investigator, not suitable for the study * In the opinion of the investigator, the subject requires surgical repair of the Carpal Tunnel Syndrome, or the symptoms will be worsen result in irreversible damage to the subject if not treated with surgical repair within 3 months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Use QtracW and NCS to evaluate the changes between pre-treatment and post-treatment in patients in both arms. | 12 weeks |
Secondary
| Measure | Time frame |
|---|---|
| use BCTQ to evaluate the efficacy of 2 arms at week 4 and at week 12. | 12 weeks |
| use VAS to evaluate the efficacy of 2 arms at week 5, 8 and 12. | 12 weeks |
| Use Quality of Life questionnaire to compare the efficacy of 2 arms at week 12. | 12 weeks |
| Evaluate the safety of 2 arms during the study period | 12 weeks |
Countries
Taiwan
Contacts
Primary ContactJia-Ying Sung, MD
Outcome results
None listed