ST-Elevation Myocardial Infarction
Conditions
Keywords
myocardial salvage, cardiovascular magnetic resonance, magnetic resonance imaging, myocardial infarction, prognosis
Brief summary
In acute myocardial infarction cardiovascular magnetic resonance imaging can retrospectively detect the myocardium at risk and the irreversible injury. This allows for quantifying the extent of salvaged myocardium after reperfusion as a potential strong end point for clinical trials and outcome. The aim of the present study is to determine the prognostic significance and determinants of myocardial salvage assessed by CMR in reperfused ST-elevation myocardial infarction (STEMI).
Interventions
OTHERmagnetic resonance imaging
magnetic resonance imaging is used for prognosis assessment
Sponsors
University of Leipzig
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* ST-elevation myocardial infarction \< 12 hours * primary percutaneous coronary intervention
Exclusion criteria
* previous myocardial infarction * prior fibrinolysis * contraindications to CMR at study entry (such as implanted pacemakers, defibrillators, claustrophobia or metallic intracranial implants)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Major adverse cardiac events | 6 months |
Secondary
| Measure | Time frame |
|---|---|
| Mortality | 6 months |
Countries
Germany
Outcome results
None listed