The Acute Effects of Coffee on Glucose Metabolism

Human Trial of the Acute Effects of Coffee on Glucose Metabolism

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00950898

Enrollment

Registered

2009-08-03

Start date

2006-11-30

Completion date

2007-06-30

Last updated

2009-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Type 2 Diabetes

Keywords

coffee, caffeine, glucose metabolism, insulin sensitivity, diabetes

Brief summary

The purpose of this study was to determine the acute effects of decaffeinated coffee, caffeinated coffee and caffeine on glucose metabolism in humans

Interventions

OTHERdecaff

2 mugs of decaffeinated coffee

OTHERcaffcoff

2 mugs of caffeinated coffee

OTHERcaffeine

2 mugs of hot water containing caffeine

OTHERplacebo

2 mugs of hot water

Study design

Allocation

RANDOMIZED

Intervention model

CROSSOVER

Primary purpose

BASIC_SCIENCE

Masking

SINGLE (Subject)

Eligibility

Sex/Gender

MALE

Age

18 Years to 35 Years

Healthy volunteers

Yes

Inclusion criteria

* healthy young males * nonsmokers * moderate alcohol users

Exclusion criteria

* not on any medications that could alter glucose metabolism * no history of blood disorders

Design outcomes

Primary

Measure	Time frame
plasma glucose levels	0, 10, 30, 60, 90, and 120 minutes.

Secondary

Measure	Time frame
plasma insulin	0, 10, 30, 60, 90, and 120 minutes

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026