ICU Cell Saver to Reduce Blood Transfusions in Cardiac

Routinely Use of CardioPAT Cell Saver in Cardiac Surgery: A Prospective Randomized Study Focused on Allogenic Blood Transfusion and Clinical Outcome

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00950547

Enrollment

350

Registered

2009-07-31

Start date

2009-08-31

Completion date

2010-01-31

Last updated

2010-01-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Blood Transfusion, Cardiac Surgery

Keywords

Blood Transfusion, Cell Saver, Cardiac Surgery, Evaluate the efficacy of cell salvage CardioPAT routinely used in cardiac surgery in reducing blood transfusions.

Brief summary

PURPOSE: Autotransfusion devices may be employed in cardiac surgery to decrease allogenic blood requirements. Limitations of previous trials include the use of cell saver systems in selected high risk patients only or the lack of blood transfusion-sparing strategies. The aim of this prospective randomized study is to evaluate the efficacy of cell salvage CardioPAT routinely used in cardiac surgery. METHODS: The investigators will randomize 350 patients in two groups: group 1 receives a CardioPAT cell saver device (175 patients), group 2 doesn't receive any cell saver device. The incidence of allogenic blood transfusion and clinical outcome in both groups are evaluated.

Interventions

DEVICECARDIOPAT

Cell Saver System at bedside for ICU stay

DEVICETraditional Chest Drains

Chest drains as usual with no possibility to reinfuse lost blood

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

ALL

Healthy volunteers

Inclusion criteria

* All patients presenting for cardiac Surgery

Exclusion criteria

* None

Design outcomes

Primary

Measure	Time frame
Number of Transfusions per patient	10 days after surgery

Secondary

Measure	Time frame
Mortality	30 days after surgery

Countries

Italy

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026