Risk Communication
Conditions
Brief summary
The purpose of this study is to test whether cautions about the evidence, in this case an open questions statement, decreases enthusiasm for drugs that are approved on surrogate outcomes (compared to patient outcomes) alone.
Interventions
OTHERPresentation of information on approval based on a surrogate outcome and levels of caution
Presentation of information that one drug is approved on a surrogate outcome only while another drug has clinical outcomes. Participants are randomized to 1 of 3 caution (e.g. open question) statements: no open question statement, non-directive open question statement or directive open question statement.
Sponsors
Attorney General Consumer & Prescriber Education Grant
White River Junction Veterans Affairs Medical Center
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Masking
SINGLE (Investigator)
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* Participants will be randomly selected from a research panel of more than 60,000 U.S. households (Knowledge Networks).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Hypothetical choice of drug approved on surrogate outcomes vs. drug known to improve patient outcomes | 0 weeks (assessed during intervention) |
Secondary
| Measure | Time frame |
|---|---|
| Strength of opinion (take or refuse doctor's recommendation) for taking the drug approved on surrogate outcomes vs. drug known to improve patient outcomes | 0 weeks (assessed during intervention) |
Outcome results
None listed