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Influence of Posture and Gas Insufflation on Perioperative Lung Function

Influence of Posture, Anesthesia and Surgical Technique on Airway Resistance of the Upper and Lower Airway and Lung Function.

Status
UNKNOWN
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT00948571
Enrollment
60
Registered
2009-07-29
Start date
2009-04-30
Completion date
2012-02-29
Last updated
2011-06-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pneumoperitoneum

Keywords

Vital capacity, FEV1, airway resistance, perioperative changes in lung function

Brief summary

Perioperative airway resistance and lung function are evaluated perioperatively in patients, who undergo surgical procedures in different postures and with or without gas insufflation into the peritoneal cavity.

Detailed description

Lung function, upper and lower airway resistance measurements are performed in patients in prone horizontal or head tilted down (40°) position. Half of the patients with head down position will have surgery in laparoscopic technique (including gas insufflation to achieve a pneumoperitoneum). Measurements are performed on the day prior to surgery, on the morning of surgery, 30 - 45 minutes, 2 hours, and 24 hours after extubation.

Interventions

None listed

Sponsors

Kliniken Essen-Mitte
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Patients older than 18 years of age. * Patients with normal lung function with respect to age, gender and weight. -Patients scheduled for Prostatectomies, robotic Prostatectomies, and open hemicolectomies.

Exclusion criteria

* Patients younger than 18 years. * Patients with pathological lung function. * Patients with with major cardiac disease.

Design outcomes

Primary

MeasureTime frame
Measurement of FEV1 (forced expiratory volume in one second) and the MEF50/MIF50 ratio18 months

Secondary

MeasureTime frame
Changes in nasal airway resistance18 months

Countries

Germany

Contacts

Primary ContactHarald Groeben, Prof. Dr.
h.groeben@kliniken-essen-mitte.de##49201174

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026