To Demonstrate the Effect of Food on the Bioavailability of Glipizide

The Effect of Food on the Bioavailability of Glipizide

Status

Completed

Phases

Phase 1

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00947024

Enrollment

Registered

2009-07-27

Start date

1993-11-30

Completion date

1993-11-30

Last updated

2017-03-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Type 2 Diabetes

Brief summary

To demonstrate the effect of food on the bioavailability of Glipizide.

Interventions

DRUG10 mg Glipizide Tablet (Geneva Pharmaceutical, Inc.), Administered Immediately After a Standard Breakfast.

DRUG10 mg Glucotrol Tablet (Roerig), Administered Immediately After a Standard Breakfast.

DRUG10 mg Glipizide Tablet (Geneva Pharmaceutical, Inc.), Administered After an Overnight Fast.

Study design

Allocation

RANDOMIZED

Intervention model

CROSSOVER

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

MALE

Age

18 Years to 50 Years

Healthy volunteers

Yes

Inclusion criteria

* No clinically significant abnormal finding on physical exam, medical history, or clinical laboratory results on screening.

Exclusion criteria

* Positive test results for HIV or hepatitis B or C. * Treatment for drug or alcohol dependence.

Design outcomes

Primary

Measure	Time frame
Bioequivalence based on AUC and Cmax	15 days

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026