Barrier Function Measurement in Dry Eye Patients After Using Systane Ultra for 30 Days

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00946777

Enrollment

Registered

2009-07-27

Start date

2009-07-31

Completion date

2009-09-30

Last updated

2016-11-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Dry Eye

Keywords

Dry Eye Signs, barrier function

Brief summary

The primary objective is to determine if there is a correlation between reductions in corneal staining and improvements in corneal barrier function.

Interventions

OTHERSystane® Ultra

Systane® Ultra 1-2 drops, 4 times per day for 30 days

Study design

Allocation

Intervention model

SINGLE_GROUP

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Patients must have moderate corneal staining and exhibit a need to use artificial tears.

Exclusion criteria

* Patients can not participate in any other ophthalmic drug or device clinical trial within 30 days of the baseline visit.

Design outcomes

Primary

Measure	Time frame
Percent change from baseline of corneal fluorescein	30 days

Secondary

Measure	Time frame
Adverse event occurence	30 Days

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026