Healthy Participants
Conditions
Brief summary
Tradition holds that the intake of different drinks with a meal has an important influence on the digestion of food and postprandial symptoms such as fullness, bloating and satiety; however this assumption have never been subjected to controlled study A classic example is the Swiss cheese fondue. The intake of white wine, tea and cherry schnapps (Kirsch) are often attributed either positive or negative effects on the gastrointestinal tract. In this study the effect of white wine vs. tea intake during and an alcoholic digestive following a high fat, high calorie Swiss fondue meal on gastric emptying and visceral perception will be investigated using a randomized, controlled study design. The fondue will be labeled with non-radioactive 13C octanoate for assessment of gastric emptying by breath-test.
Interventions
DIETARY_SUPPLEMENTIngestion of white wine vs. tea during and an alco
4 x 50ml glasses of white wine (12% alcohol) or tea will be taken according to a randomization scheme After the meal 1 x 20ml of Kirsch (40% alcohol) or tea will be taken
Sponsors
COOP
University of Zurich
Study design
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
HEALTH_SERVICES_RESEARCH
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
19 Years to 60 Years
Healthy volunteers
No
Inclusion criteria
• able to communicate well with the investigators and provide written consent • Body Mass Index: 19-30 kg/m2
Exclusion criteria
• physical co-morbidity requiring active treatment * psychiatric (DSM IV) disorders limiting the ability to comply with study * use of medications influencing upper GI motility * evidence of current drug or alcohol abuse * history of gastrointestinal disease or surgery except appendicectomy or hernia repair
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Effect of white wine vs. tea on gastric emptying | 4 hours |
Countries
Switzerland
Outcome results
None listed