Airway Complication Which Require Any Intervention
Conditions
Brief summary
Airway complications are a significant cause of morbidity after lung transplantation (LTx). Bronchoscopic evaluation may help to identify risk factors for requiring interventions later.
Detailed description
The investigators evaluated lung transplant recipients prospectively. Adult patients surviving 90 day after LTx will be included. The investigators propose a classification of airway healing based on the endoscopic bronchial appearances at days 7, 14, 21, 90, 180 and 365 after LTx. A score system including mucosal healing, full tissue necrosis (=dehiscence), lose sutures, fibrin plugs, polyps and malacia will be developed (max. score 8 points/date). Endoscopic findings will be correlated with the development of obstructive airway complications (OAC, requiring \>1 intervention). Afterwards the new score system will be applied prospectively in the patients.
Interventions
None listed
Sponsors
Thomas Fuehner
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 80 Years
Healthy volunteers
No
Inclusion criteria
* 3 month survivor after LTx * no OAC
Exclusion criteria
\-
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Primary endpoint of this study was any obstructive airway complication (AC) which required desobliterative intervention. | 1 year |
Secondary
| Measure | Time frame |
|---|---|
| secondary endpoint included anastomosis-related death. | 1 year |
Countries
Germany
Outcome results
None listed