Ibuprofen Suppositories Administration in Infants and Children

Ibuprofen Suppositories Administration for Fever Treatment in Infants and Children

Status

UNKNOWN

Phases

Phase 4

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00938509

Enrollment

100

Registered

2009-07-14

Start date

2009-07-31

Completion date

2009-12-31

Last updated

2009-07-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Fever

Keywords

IBUPROFEN, CHILDREN, FEVER

Brief summary

The study will evaluate the efficacy of Ibuprofen administered as suppositories in the treatment of fever in infants and children. Ibuprofen as suppositories is not yet registered in Israel, although widely used in Europe.

Detailed description

The drug will be used in 100 consecutive infants and children admitted with fever at the pediatric ER of the Soroka Medical Center. The information on the drug efficacy will be collected in appropriate parental questionnaires.

Interventions

DRUGibuprofen suppositories

5-10 mg/kg/day-suppositories

Study design

Allocation

RANDOMIZED

Intervention model

SINGLE_GROUP

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

6 Months to 12 Years

Healthy volunteers

Inclusion criteria

* Infants and children with rectal temperature \> 38.5 C

Exclusion criteria

* Infants \< 6 months of age

Design outcomes

Primary

Measure	Time frame
Fever decrease	1 day

Countries

Israel

Contacts

Primary ContactEUGENE LEIBOVITZ, MD

eugenel@bgu.ac.il972-8-6244065

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026