Stroke
Conditions
Keywords
cerebrovascular accident, bone, muscle, vibration
Brief summary
The overall aim of the proposed study is to determine whether whole body vibration is beneficial in promoting bone health, physical fitness and neuromotor performance in patients with chronic stroke. Subjects in the experimental group will undergo whole body vibration therapy (1 session per day, 3 sessions per week) for 8 weeks. The vibration frequency used in this study will be 30Hz. The total duration of exposure to vibration for the experimental group will be 10 minutes. While standing on the vibration platform, patients will be instructed to repeat the following set of light exercises: (1) light squatting,(2) deep squatting, (3) side-to-side weight-shift, (4) Forward and backward weight-shift, (5) forward lunge, (6) marching on the spot. The control exercise group, on the other hand, will perform the same exercise program on the platform, but no vibration will be given. The training will be conducted by a qualified personnel with physiotherapy background. The outcome measurement will be performed 4 times: (1) immediately before the commencement of intervention, (2) immediately after termination of treatment, (3) at 1 month after termination of treatment. Each subject will be evaluated for bone markers, leg muscle strength, balance, spasticity, and walking ability.
Interventions
Experimental group: One session per day, 3 sessions per week, for consecutive 8 weeks. The total duration of whole body vibration therapy will be about 10 minutes per session.
DEVICEExercise on the vibration platform with the device turned off
Control group: One session per day, 3 sessions per week, for consecutive 8 weeks. The subjects will perform the same exercises on the vibration platform but no vibration will be applied.
Sponsors
The Hong Kong Polytechnic University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* a diagnosis of stroke more than 6 months * medically stable * able to understand verbal commands * Abbreviated mental test score 6 or above * age \>18 * able to stand with or without aids for at least 1.5 minutes
Exclusion criteria
* neurological conditions other than stroke * significant musculoskeletal conditions (e.g. amputations) * metal implants in the lower extremity * previous fracture of the lower extremity * are currently taking bone resorption inhibitors or were taking the same before stroke. * significant peripheral vascular disease * vestibular disorders * pregnancy * Other serious illnesses that preclude the person from participating in the study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Paretic knee concentric muscle strength | pre-test (week 0) |
Secondary
| Measure | Time frame |
|---|---|
| Non-paretic concentric knee muscle strength | Pre-test (week 0) |
| Non-paretic knee concentric muscle strength | Post-test (week 8) |
| Paretic knee eccentric muscle strength | pre-test (week 0) |
| Non-paretic knee eccentric muscle strength | Pre-test (week 0) |
| Paretic knee isometric muscle strength | Pre-test (week 0) |
| Non-paretic knee isometric muscle strength | Pre-test (week 0) |
| Limit of stability test | Pre-test (week 0) |
| Berg balance test | Pre-test (week 0) |
| Activities-specific Balance Confidence Scale | Pre-test (week 0) |
| Self-selected gait velocity | Pre-test (week 0) |
| Bone formation marker level | pre-test (week 0) |
| Bone resorption marker level | pre-test (week 0) |
| fall rate | 6 months after termination of treatment |
| Knee spasticity | Pre-test (week 0) |
| Ankle spasticity | Pre-test (week 0) |
| Level of satisfaction | Post-test (week 8) |
| Six Minute Walk Test | Pre-test (week 0) |
Countries
China
Outcome results
None listed