Injury of Duodenum, Pancreatic Injury
Conditions
Keywords
laparotomy, duodenal injury, pancreatic injury, trauma
Brief summary
The management of significant duodenal injuries and combined duodenal-pancreatic injuries continues to be challenging and controversial, and several techniques have been advocated over the years. One technique surgeons employ is the damage control/planned reoperation strategy. At the trauma center, the advent of damage control and other planned re-operation strategies has resulted in an evolution in the investigators management of duodenal lacerations and combined duodenal-pancreatic injuries. In this retrospective review, the investigators intend to quantify the investigators change in practice and to report its outcome compared to previous practice. Using the OHSU Trauma Laparotomy Outcomes Database, the investigators will identify all patients receiving trauma laparotomy for a duodenal or duodenal/pancreatic injury for a period of 20 years, from 1989-2009. A number of data points will be retrieved from patients' medical records, including but not limited to grade of duodenal injury, mechanism of injury, Injury Severity Score, and others.
Detailed description
The management of significant duodenal injuries and combined duodenal-pancreatic injuries continues to be challenging and controversial. Several techniques have been advocated over the years to prevent the dreaded complications of repair breakdown, fistulization, and intra-abdominal sepsis. These include duodenal diverticulization, triple tube ostomy, tube duodenostomy, and pyloric exclusion. These techniques are all designed to decompress, heal without undue intraluminal pressure or flow. Recently, surgeons have questioned whether aggressive adjunctive diversion is truly necessary, especially for less severe injuries, and many have noted complications associated with the reconstructions apart from the injury. An alternative to routine diversion/decompression/exclusion is the damage control/planned reoperation strategies following laparotomy for severe visceral injuries that have become prevalent in the past two decades. Instead of performing a primary duodenal repair with enteral diversion or decompression in a single operation, many surgeons employ a surveillance and touch-up strategy over the course of 2-4 abdominal explorations. The abdominal fascia is not closed until the healing phase has commenced and the surgeon feels confident the repair will hold. At the trauma center, the advent of damage control and other planned re-operation strategies as resulted in an evolution in our management of duodenal lacerations and combined duodenal-pancreatic injuries. The investigators perform noticeably fewer decompression, diversion, or exclusion procedures and have increasingly relied on serial abdominal explorations for surveillance of the repair. In this retrospective review, we intend to quantify our change in practice and to report its outcome compared to previous practice. Using the OHSU Trauma Laparotomy Outcomes Database, we will identify all patients receiving trauma laparotomy in which a duodenal or combined duodenal-pancreatic injury was identified in a 20-year period from 1989-2009. The medical records of these patients will be reviewed to confirm duodenal injury and to tabulate other factors. The patients will be categorized based on management of the duodenal injury, e.g. primary repair, decompression, diversion, or exclusion. Patients will also be categorized according to laparotomy strategy, e.g. damage control, planned reoperation, or primary fascial closure without planned reoperation. Duodenal-related complications will be tabulated and the various groups compared. The investigators anticipate including up to 50 patients.
Interventions
None listed
Sponsors
Study design
Eligibility
Inclusion criteria
* Trauma patients who received a trauma laparotomy for a duodenal or combined duodenal/pancreatic injury
Exclusion criteria
* None
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Duodenal-related Complications | 20 years | Duodenal-related complications including leak, obstruction, and abscess |
Countries
United States
Participant flow
Recruitment details
Inpatients requiring laparotomy for trauma with duodenal injury years 1989 - 2009
Participants by arm
| Arm | Count |
|---|---|
| Injury Management Patients with full thickness duodenal laceration undergoing laparotomy and surviving more then 72 hours at our level 1 trauma center in the years 1989-2009. Patients requiring pancreaticoduodenectomy were excluded. | 41 |
| Total | 41 |
Baseline characteristics
| Characteristic | Injury Management |
|---|---|
| Age Continuous | 34 years STANDARD_DEVIATION 18 |
| Region of Enrollment United States | 41 participants |
| Sex: Female, Male Female | 19 Participants |
| Sex: Female, Male Male | 22 Participants |
Adverse events
| Event type | EG000 affected / at risk |
|---|---|
| deaths Total, all-cause mortality | — / — |
| other Total, other adverse events | 0 / 41 |
| serious Total, serious adverse events | 0 / 41 |
Outcome results
Duodenal-related Complications
Duodenal-related complications including leak, obstruction, and abscess
Time frame: 20 years
Population: Patients with duodenal related complications
| Arm | Measure | Value (NUMBER) |
|---|---|---|
| No Diversion Decompression or Exclusion | Duodenal-related Complications | 13 percentage of subjects |
| Diversion Decompression or Exclusion | Duodenal-related Complications | 11 percentage of subjects |
| Damage Control | Duodenal-related Complications | 8 percentage of subjects |
| Fascial Closure | Duodenal-related Complications | 19 percentage of subjects |