Randomized Clinical Trial of Treatment for Temporomandibular Joint (TMJ) Disc Displacement

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00936338

Enrollment

Registered

2009-07-10

Start date

2006-01-31

Completion date

2006-12-31

Last updated

2009-07-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Herniated Disk, Temporomandibular Disorders

Keywords

anterior disc displacement without reduction of temporomandibular disorders

Brief summary

The effectiveness of physical therapy for treatment of anterior disc displacement without reduction of temporomandibular disorders has not been well defined. This study compared the treatment method with conservative splint therapy. Fifty two subjects were assigned at random to either of two treatment groups: one is a splint treatment group, and the other is a joint mobilization self exercise group. Each treatment was evaluated using four outcome variables: (i) maximum mouth opening range without and (ii) with pain, (iii) present pain intensity, and (iv) limitation of daily activities. All outcome variables were significantly improved after eight-week of treatment in the exercise group. Meanwhile, the splint treatment improved three variables, other than mouth opening with pain; however, the degree of improvement was less than that seen in the exercise group. This result demonstrates that the joint mobilization self exercise improves jaw function and relieves pain as compared to the splint treatment.

Interventions

BEHAVIORALsplint and joint mobilization self exercise

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Inclusion criteria

* (1) male or female over 18 years old; * (2) with mouth opening pain on the TMJ affected side; * (3) over two weeks after the onset of ADDwoR; * (4) with maximum mouth opening of less than 40 mm; and * (5) MRI-confirmed ADDwoR. The

Exclusion criteria

* (1) unwilling or unable to receive splint and/or exercise therapy; * (2) with systemic bone or joint disease, * (3) regular medication such as analgesics, anti-anxiety drugs, antidepressants and psychotropics; and * (4) missing teeth and/or a removable denture but having a fixed partial denture restoration over one year.

Design outcomes

Primary

Measure	Time frame
(i) maximum mouth opening range without and (ii) with pain, (iii) present pain intensity, and (iv) limitation of daily activities	0, 4 and 8 week

Countries

Japan

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026