Prostatic Neoplasms
Conditions
Brief summary
The objective of this study is to evaluate imaging quality and correlation with histopathology in prostate cancer.
Detailed description
The objective of this study is to evaluate of the potential of endorectal 3T MRI for the staging of prostate cancer before prostatectomy or recurrence of prostate cancer after prostatectomy
Interventions
DEVICEMR imaging with endorectal coil
MR imaging with endorectal coil
DEVICEMRI with endo-rectal coil
MRI with endo-rectal coil
Sponsors
Sheba Medical Center
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
MALE
Age
18 Years to 80 Years
Healthy volunteers
No
Inclusion criteria
* Age of patients: up to 80 years. * Men scheduled for radical prostatectomy due to prostate cancer or men post radical prostatectomy with suspicion of recurrence. * Patients who are able and willing to give consent and able to have an MRI examination.
Exclusion criteria
* Contraindications to MRI including: claustrophobia, weight over 120 kg, implanted ferromagnetic materials or foreign objects, and known intolerance to the MRI contrast agent (e.g. Gadolinium or Dotarem) * Individuals who are not able or willing to tolerate the required prolonged stationary supine position during imaging (approximately 1 hr.) * Any rectal pathology preventing probe insertion, (as active proctitis, active ulcerative colitis, fissure ani) * Any spinal pathology that prohibits maintaining supine position for an hour * Patients with documented myocardial infarction within one month of protocol entry, and patients with cardiac pacemakers * Severe cerebrovascular disease (multiple CVA or CVA within 6 months)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| • MRI and pathology correlation | 2 years |
Countries
Israel
Outcome results
None listed