Differential Effects of a Diet Supplementation With Plant Sterol Esters on Human Monocytes

Differential Effects of Functional Foods Supplemented With Plant Sterol Esters on Blood Cells and Serum Parameters.

Status

UNKNOWN

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00928616

Acronym

PSE-MO

Enrollment

Registered

2009-06-26

Start date

2009-04-30

Completion date

2009-06-30

Last updated

2009-06-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hyperlipidemia

Keywords

hyperlipidemia, plant sterols, monocytes

Brief summary

The purpose of this study is to evaluate the effects of a diet supplementation with plant sterol esters on serum lipids, plant sterol concentrations and monocyte subpopulations.

Detailed description

This study investigates effects of a diet supplementation with plant sterol esters on serum lipids, plant sterol concentrations and monocyte subpopulations.

Interventions

DIETARY_SUPPLEMENTmargarine + plant sterol esters

margarine supplemented with plant sterol esters (3g/day) over the time period of 4 weeks

DIETARY_SUPPLEMENTmargarine (placebo)

non-sterol ester supplemented margarine

Study design

Allocation

RANDOMIZED

Intervention model

CROSSOVER

Primary purpose

TREATMENT

Masking

QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

18 Years to 65 Years

Healthy volunteers

Yes

Inclusion criteria

* healthy individuals without known cardiovascular diseases

Exclusion criteria

* drugs that interfere with cholesterol metabolism * other use of dietary supplements * vegetarianism

Design outcomes

Primary

Measure	Time frame
monocyte subpopulations	4 weeks

Secondary

Measure	Time frame
serum parameters (lipids, plant sterol concentrations, inflammation parameters)	4 weeks

Countries

Germany

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026