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The Danish Childhood Obesity Biobank

The Danish Childhood Obesity Biobank

Status
UNKNOWN
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT00928473
Enrollment
5000
Registered
2009-06-26
Start date
2009-01-31
Completion date
2025-12-31
Last updated
2020-11-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cardiovascular Diseases, Metabolic Disease, NAFLD, Non-alcoholic Fatty Liver Disease, Obesity

Brief summary

The Danish Childhood Obesity Biobank aims to produce a scientific platform for research in obesity: Bio-clinical data are collected from two cohorts - an obesity clinic cohort and a population-based cohort. The biobank thus facilitates translation between research and clinical practice of obesity treatment and related complications.

Detailed description

The Danish Childhood Obesity Biobank collects data from two cohorts - an obesity clinic cohort and a population-based cohort, of which the latter functions as a reference group. The biobank continuously and longitudinally includes clinical data and biological samples from children and adolescents in obesity treatment. The population-based cohort has been recruited in a cross-sectional manner from Danish schools, high schools, and dentistries. Data included in the biobank include venous blood samples, stool, urine, saliva, anthropometrics, body composition by dual-energy X-ray absorptiometry, magnetic resonance imaging and spectroscopy, and genetic markers among others. The data are stored in a central secured electronic database and biological materials are stored in -80-degree Celsius freezers until analyses. To date, the Danish Childhood Obesity Biobank have included data from more than 5250 children, adolescents and adults from the obesity clinic cohort and more than 4200 from the population-based cohort.

Interventions

BEHAVIORALA family-centered, multidisciplinary obesity treatment program

The obese children will start a treatment for obesity in the Children's Obesity Clinic. This treatment includes lifestyle counseling, objective examination, weight-controls, visiting a psychologist, visiting a dietician and blood samples, DXA-scan, eventually MRI.

Sponsors

University of Copenhagen
CollaboratorOTHER
Steno Diabetes Center Copenhagen
CollaboratorOTHER
Holbaek Sygehus
CollaboratorOTHER
Zealand University Hospital
Lead SponsorOTHER

Study design

Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
HEALTH_SERVICES_RESEARCH
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
2 Years to 100 Years
Healthy volunteers
No

Inclusion criteria

* 2- 100 Years old * Adipose, BMI \> 90 % percentile

Design outcomes

Primary

MeasureTime frame
Weightloss, changes in blood parameters and in fatty liver developement.continuously

Countries

Denmark

Contacts

Primary ContactJens-Christian Holm, Ph.d., MD
jhom@regionsjaelland.dk

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Mar 14, 2026