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The Spectralis-Cirrus Study

Comparison of Quality and Reproducibility of Retinal Thickness Measurements in Two Spectral Domain OCT- Machines

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT00927303
Enrollment
110
Registered
2009-06-24
Start date
2009-07-31
Completion date
2009-12-31
Last updated
2010-06-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Exudative Age Related Macular Degeneration

Keywords

retinal thickness, threshold algorithm, optical coherence tomography

Brief summary

Retinal thickness measurement is one of the most important examinations in the follow up of exudative age-related macular degeneration. Prior studies have shown that there are a series of algorithm line failures in OCT examinations. This study is conducted to compare the quality of the examinations of to different spectral domain OCT machines concerning the positioning of algorithm lines. Furthermore the reproducibility of the examinations id tested, both machines provide different techniques to guarantee that in repeated examinations the same location is examined.

Interventions

DEVICECirrus-Spectralis

512x128 cúbe program of Cirrus OCT first retinal volume 121 line of Spectralis OCT thereafter

DEVICESpectralis-Cirrus

retinal volume program 121 lines Spectralis OCT first 512x128 program Cirrus OCT thereafter

Sponsors

The Ludwig Boltzmann Institute of Retinology and Biomicroscopic Laser Surgery
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
50 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Exudative age related macular degeneration

Exclusion criteria

* Macular pathologies other than age related macular degeneration (diabetic maculopathy, macular pucker, macular hole, * Visualization of the macula not possible (dens cataract, vitreous haemorrhage) * Not consented patients

Design outcomes

Primary

MeasureTime frame
Number of examinations with correctly set threshold algorithm lines1 day

Secondary

MeasureTime frame
Differences of mean retinal thickness in the central region1 day
Differences of retinal volume1 day
Distance acuity1 day
Age1 day
Classification of the lesion1 day

Countries

Austria

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026