Healthy
Conditions
Keywords
Healthy volunteers
Brief summary
The hypothesis is that liquorice lowers plasma potassium. This study aims to elucidate the dose-response of this effect with two doses of liquorice (66 grams or 102 grams) per day for two weeks.
Interventions
OTHERLiquorice 66 g/day
Liquorice 66 g/day for two weeks
OTHERLiquorice 102 g/day
Liquorice 102 g/day for two weeks
Sponsors
University of Oulu
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 40 Years
Healthy volunteers
Yes
Inclusion criteria
* healthy volunteers * age 18-40
Exclusion criteria
* any continuous medication * hypertension or hypotension * allergy to liquorice * pregnancy or lactation * difficult venipuncture * drug or alcohol abuse * participation in pharmaceutical trial
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Change in plasma potassium | 1 week, 2 weeks |
Countries
Finland
Outcome results
None listed