Chronic Nonspecific Low Back Pain
Conditions
Keywords
low back pain, motor control, cortical regulation, transcranial magnetic stimulation
Brief summary
The purpose of this study is to explore the cortical regulation of the paraspinal muscles in chronic low back pain. These (possible) changes in regulatory mechanisms are being compared to other motor control tests in order to determine whether correlations are found. Furthermore the patients are being treated with repetitive transcranial magnetic stimulation (rTMS) and tested afterwards. The purpose is to find out if rTMS-therapy is capable of normalizing motor control deficits.
Interventions
DEVICEtranscranial magnetic stimulation
rTMS therapy daily for two weeks, five times per week each lasting for half an hour
Sponsors
Kuopio University Hospital
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
BASIC_SCIENCE
Masking
SINGLE (Subject)
Eligibility
Sex/Gender
MALE
Age
25 Years to 50 Years
Healthy volunteers
Yes
Inclusion criteria
* chronic nonspecific low back pain for at least six months * male gender * age 25-50 yrs * average pain during last week 4-8/10 by VAS * Oswestry disability index 20-80 %
Exclusion criteria
* former spinal operations * rheumatic disease, marked spondylolysis and -olisthesis, other diseases that markedly reduce physical or psychological performance, history of epilepsy, history of taking epileptic or strong opioid drugs
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Correlation between cortical activity and other motor control tests | day 1 and day 19 |
Secondary
| Measure | Time frame |
|---|---|
| The effect of rTMS-therapy for clinical outcome and motor control tests | day 19, 1 month, 2 months, 1 year |
Countries
Finland
Outcome results
None listed