Automating Breast Radiation Therapy (RT)

Automating the Breast Radiation Therapy Process to Improve Efficiency

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00923871

Enrollment

160

Registered

2009-06-18

Start date

2009-06-30

Completion date

2016-04-29

Last updated

2022-10-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Breast Cancer

Keywords

CBCT, Breast Cancer

Brief summary

Breast radiation treatment is planned from a Computed Tomography (CT) scan. This study is designed to investigate a method to reduce the time between the planning of radiation treatment and its actual start by automating the intensity-modulated radiation therapy (IMRT) planning process. The investigators plan to examine data from another scan called Cone Beam Computed Tomography (CBCT). A CBCT scan provides similar information to a conventional CT scan, however the images for CBCT are acquired at the treatment unit (linear accelerator used for treatment). Using these x-ray pictures of patients, the study team consisting of a radiation oncologist, a medical physicist and a radiation therapist will create a custom treatment plan unique to each patient. By doing this, the investigators hope to reduce the amount of time spent waiting for treatment and the number of hospital visits for patients in the future.

Interventions

PROCEDURECone Beam CT

Patients will also have a CBCT scan when they are having their first IMRT treatment.

Study design

Allocation

Intervention model

SINGLE_GROUP

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

FEMALE

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Patients with breast cancer who will receive standard two-field tangential whole breast radiation therapy with dose prescription of 4240 cGy in 16 fractions, 5000 cGy in 25 fractions or 4000 cGy in 16 fractions. * Patients with any stage of breast cancer. * Patients with prior treatment such as surgery or chemotherapy for any type of cancer. * Able to provide a written informed consent. * 18 years of age or older.

Exclusion criteria

* \< 18 years of age. * Unable to provide informed consent. * Males. * Patients who received partial breast radiation and not the standard dose. * Patients who will not receive 4240 cGy in 16 fractions, 5000 cGy in 25 fractions, or 4000 cGy in 16 fractions.

Design outcomes

Primary

Measure	Time frame
To generate on-line IMRT treatment plans using automated tools based on CBCT images acquired at the treatment unit.	3 years

Countries

Canada

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026