Skip to content

A Study of a Potential Mechanisms of Spinal Manipulation in the Treatment of Low Back Pain

Immediate Effect of Physical Interventions for Low Back Pain

Status
Completed
Phases
Phase 1
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT00922220
Enrollment
94
Registered
2009-06-17
Start date
2004-10-31
Completion date
2008-11-30
Last updated
2011-12-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Low Back Pain

Keywords

low back pain, spinal manipulation, central sensitization, manual therapy

Brief summary

The purpose of this study was to determine the immediate effect of 3 common physical therapy interventions for people experiencing low back pain on the perception of thermal pain. Additionally, the investigators wished to determine the influence of psychological factors related to fear and anxiety on their findings and to determine whether the effects of the individual interventions were local (specific to the area of application) or global (influenced regions away from the area of application).

Interventions

Participants rode a stationary bike for five minutes

OTHERlumbar extension exercise

Participants performed four sets of fifteen lumbar extension exercises over fifteen minutes

participants received spinal manipulative therapy to the low back

Sponsors

University of Florida
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
18 Years to 60 Years
Healthy volunteers
Yes

Inclusion criteria

* ages eighteen to sixty * currently experiencing low back pain OR currently not experiencing low back pain and have not had an episode for the prior six months

Exclusion criteria

* non-English speaking * systemic medical conditions (e.g. diabetes, hypertension) * current use of psychiatric medication * pregnancy * signs and symptoms indicative of nerve root compression (reflex change, myotomal weakness, or sensation change) * history of surgery to the low back

Design outcomes

Primary

MeasureTime frame
Numeric Rating ScalePrior to and immediately following assigned intervention

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026