Liver Neoplasms
Conditions
Keywords
malignancy, liver, microwave, surgery
Brief summary
Microwave ablation (MWA) is the most recent development in the field of local ablative therapies. The aim of this study was to evaluate the variability and reproducibility of single-probe MWA versus radiofrequency ablation (RFA) of metastatic liver tumours smaller than 3 cm in patients without underlying liver disease.
Interventions
DEVICEMicrowave ablation
Liver tumors are destructed/ablated using single-probe microwave energy device
DEVICERadiofrequency ablation
Liver tumors are destructed/ablated using radiofrequency energy device
Sponsors
University Hospital, Gasthuisberg
Study design
Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 90 Years
Healthy volunteers
No
Inclusion criteria
* Unresectable metastatic liver cancer * No invasion of major biliary structures * No invasion of major vascular structures * ASA score \< 4 * WHO score 0-1 * Pre-operative chemotherapy is allowed
Exclusion criteria
* Resectable liver metastases * Life expectancy less than 3 months * Patients with cardiac pacemaker, cerebral aneurysm clips, implanted electronic instruments or other metal materials * Coagulopathy with platelet count less than 50000 * Active infectious disease * Age below 18 years * Pregnancy of breastfeeding
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Variability of ablation diameters | within the first 7 days and 3 months after surgery |
Countries
Belgium
Outcome results
None listed