Biospecimen Repository for Cardiac Arrhythmias at the Cleveland Clinic

Cleveland Clinic Arrhythmia Biospecimen Repository (Cleveland Clinic Arrhythmia BioBank)

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT00921986

Enrollment

2000

Registered

2009-06-17

Start date

2009-03-01

Completion date

2035-12-01

Last updated

2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Arrhythmias, Cardiac

Keywords

genetics, biorepository, cardiac death, atrial fibrillation, ventricular fibrillation, ventricular tachycardia, supraventricular tachycardias, premature ventricular complexes, premature atrial complexes, atrioventricular and intraventricular blocks, sinus node dysfunction, syncope, vasovagal reactivity, postural orthostatic tachycardia syndrome

Brief summary

Biorepository of blood and or tissue samples from patients presenting with cardiac arrhythmia syndromes.

Detailed description

The long-term objective of this research is to find genes and biologic pathways causing arrhythmia syndromes and other diseases or conditions. In order to achieve this objective the investigators will collect comprehensive phenotypic data and corresponding blood and/or tissue samples into a biorepository registry of patients, presenting for cardiac arrhythmia evaluation and/or treatment, and control subjects without arrhythmias. This biorepository will be composed of two parts: 1) An Arrhythmia Biorepository of blood and tissue from patients undergoing arrhythmia procedures, cardiac surgery, or inpatient or outpatient evaluations for arrhythmias, and 2) A Collaborative Sample Biorepository for de-identified samples and data from outside institutions and clinical trials.

Interventions

None listed

Study design

Observational model

CASE_CONTROL

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Yes

Inclusion criteria

* Male or female at least 18 years old * Subjects with a history of or current cardiac arrhythmia, family members of subjects with cardiac arrhythmias, or no cardiac arrhythmia if a Control Subject.

Exclusion criteria

* Subjects previously enrolled in the Arrhythmia BioBank

Design outcomes

Primary

Measure	Time frame	Description
Genetic variants associated with arrhythmias	Baseline	Genome-wide association study of arrhythmias

Countries

United States

Contacts

CONTACTMina K. Chung, MD

chungm@ccf.org216.444.2290

PRINCIPAL_INVESTIGATORMina K. Chung, MD

The Cleveland Clinic

Outcome results