Delirium
Conditions
Keywords
Hypnotics and Sedatives, Respiration, Artificial, Ventilators, Mechanical, Critical care, Intensive care
Brief summary
The overall purpose of this trial is to assess the relationship between a daily awakening from sedation and the prevalence of delirium, and in doing so better characterize delirium in the ICU.
Detailed description
This is a single center, observational, cross-over design study assessing the impact of daily awakening from sedation on delirium in the ICU. Enrolled patients will receive a daily baseline delirium assessment using the CAM-ICU tool before the awakening from sedation and an assessment during the awakening from sedation. Each patient will thus serve as their own controls for these interventions.
Interventions
None listed
Sponsors
University of Chicago
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* \> 18 years old * intubated and mechanically ventilated * receiving sedative and/or analgesic medication * candidate for daily awakening from sedative and/or analgesic medication
Exclusion criteria
* primary neurologic disease (stroke, seizure, elevated ICP) * post cardiac arrest * do not speak English (assessment only English language validated)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Delirium | Daily |
Secondary
| Measure | Time frame |
|---|---|
| ICU admitting diagnosis | At enrollment |
| Medications | Daily |
| Ventilator free days (or first 28) | At 28 days post-intubation |
| Days to discharge | At discharge |
| Survival | At discharge |
| ICU complications | Daily |
Other
| Measure | Time frame |
|---|---|
| survival | 1 year |
| institution free days | 1 year |
Countries
United States
Outcome results
None listed