Cancer Cachexia, Pancreatic Cancer
Conditions
Keywords
parenteral nutrition, cancer cachexia, pancreatic cancer
Brief summary
The purpose of this study is to determine whether the additional nutrition support is improving the nutritional status of patients suffering cancer caxechia or not.
Detailed description
To examine the impact of additional parenteral nutrition (APN) we prospective evaluated 32 pts suffering APC and progressive cachexia. This assay is based on a bioelectrical impedance analysis (BIA) as a proven tool for nutritional investigation in patients with chronic disease. Phase angle, determined by BIA, has been found to be a prognostic indicator in several chronic and malignant conditions, such as HIV, liver cirrhosis, chronic obstructive pulmonary disease lung cancer and pancreatic cancer.
Interventions
DIETARY_SUPPLEMENTparenteral nutrition
25kcal/kg bw with parenteral nutrition
Sponsors
Fresenius AG
CONKO-Studiengruppe
Study design
Allocation
NON_RANDOMIZED
Intervention model
SINGLE_GROUP
Primary purpose
SUPPORTIVE_CARE
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* histological proved pancreatic cancer * progressive cancer cachexia * refractive to enteral supplementation * informed consent
Exclusion criteria
* prefinal status * septic disease
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| nutritional status presented by phase angle | 12 weeks |
Secondary
| Measure | Time frame |
|---|---|
| quantity of port infections, quantity of oedema, quantity of diarrhea | 12 weeks |
Countries
Germany
Outcome results
None listed