Prospective Evaluation of the Resection Margins and the Ganglionic Status Using a Quality Standard Resection for Adenocarcinoma of the Head of the Pancreas

Prospective Evaluation of the Resection Margins and the Ganglionic Status Using a Quality Standard Resection for Adenocarcinoma of the Head of the Pancreas.

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00918853

Acronym

MRP

Enrollment

156

Registered

2009-06-11

Start date

2008-08-31

Completion date

2012-05-31

Last updated

2015-03-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Adenocarcinoma, Pancreas

Keywords

pancreas, adenocarcinoma

Brief summary

This multicentric prospective study evaluates the role of the margins resection and the ganglionic status when using a quality standard for the resection of adenocarcinoma of the head of the pancreas.

Detailed description

Primary objective: * Evaluation of the prognosis role of the invasion of the margins on the overall survival after a standard resection of adenocarcinoma of the head of the pancreas. Secondary objectives: * Evaluation of the prognosis role of the invasion: * Of margins on the overall survival. * Of each margins (distal pancreatic margin, gastric, posterior, retro-venous, retro-arterial) on the overall survival. * Of the ganglionic group of the superior mesenteric artery and the other nodes.

Interventions

PROCEDUREresection of adenocarcinoma of the head of the pancreas

quality standard for the resection of adenocarcinoma of the head of the pancreas

Study design

Allocation

Intervention model

SINGLE_GROUP

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* A head of the pancreas tumor compatible with adenocarcinoma diagnosis * tumor apparently removable * patient aged from 18 to older * signed consent Non inclusion criteria: * pregnancy, breast feeding * patient in an urgency situation or patient with legal protection

Exclusion criteria

after surgery: * tumor other than adenocarcinoma of the head of the pancreas. * analysis of the margins not done with the defined criteria * nonadhesion to the surgical protocol

Design outcomes

Primary

Measure	Time frame
Prognostic value of the invasion of the margins measured in millimetres on the overall survival	4 years

Secondary

Measure	Time frame
Relapse free survival: time between surgery and relapse or a right censure. The relapse is determined by clinical examination, biologic examination and imaging, which reveals metastasis or an isolated local relapse	4 years

Countries

France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 26, 2026