Late Onset Postoperative Nausea and Vomiting

Late Onset Postoperative Nausea and Vomiting Following Strabismus Surgery in Pediatric.What Combination is Better

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00918190

Enrollment

Registered

2009-06-11

Start date

2009-06-30

Completion date

2010-12-31

Last updated

2021-10-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative Nausea and Vomiting

Keywords

Postoperative nausea and vomiting, Pediatric, Strabismus, Late onset postoperative nausea and vomiting

Brief summary

The purpose of this trial is to study the effects of different combinations of antiemetics on the incidence of late onset postoperative nausea and vomiting.

Detailed description

The authors will study the effect of many antiemetics on the occurrence of nausea and vomiting following strabismus surgery in pediatrics.

Interventions

DRUGPlacebo

Saline

DRUGOndansetron, Dexamethasone

Use of ondansetron and dexamethasone as combined antiemetics

DRUGMidazolam, dexamethasone

use of midazolam and dexamethasone as combined antiemetic

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

PREVENTION

Masking

DOUBLE (Subject, Caregiver)

Eligibility

Sex/Gender

ALL

Age

4 Years to 12 Years

Healthy volunteers

Inclusion criteria

* children undergoing elective strabismus surgery under general anesthesia

Exclusion criteria

* children experienced retching or vomiting * children who have taken anti-emetic medications, antihistaminics, steroids, or psychoactive drugs within 24 hours before surgery

Design outcomes

Primary

Measure	Time frame
Efficacy of antiemetics combination	3 days

Countries

Saudi Arabia

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026