Periodontitis
Conditions
Brief summary
The purpose of this study is to evaluate clinical result including plaque index, gingival inflammation, bleeding score, pocket depth reduction and clinical attachment level gain after used locally-delivered gel containing Camella sinensis extracts as an adjunctive treatment in periodontal therapy
Interventions
DRUGCamella sinensis gel
clinical effect of locally-delivered gel between Camella sinensis and placebo
Sponsors
Mahidol University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
TRIPLE (Subject, Caregiver, Investigator)
Eligibility
Sex/Gender
ALL
Age
34 Years to 74 Years
Healthy volunteers
Yes
Inclusion criteria
* subjects have sound tooth with pocket depth = or \> 5 mm. without caries, restoration, mobility and furcation involvement * no systemic complicated factors * no allergy to green tea or product of green tea * signing in informed consent form
Exclusion criteria
* smoking * pregnancy or lactation * antibiotic premedication or antibiotic intake in previous 3 month
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| pocket depth reduction, clinical attachment level gain, gingival index, bleeding score | baseline, 1, 3 and 6 month after gel had loaded |
Secondary
| Measure | Time frame |
|---|---|
| plaque index | baseline, 1, 3, and 6 month after gel had loaded |
Outcome results
None listed