Prokinetic Drugs and Enteral Nutrition

Effect of Prokinetic Drugs During the Administration of Enteral Nutrition

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT00916591

Acronym

prokinetics

Enrollment

Registered

2009-06-09

Start date

2009-09-30

Completion date

Unknown

Last updated

2009-06-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Critically Ill, Enteral Nutrition

Keywords

gastroesophageal reflux, respiratory aspiration

Brief summary

The purpose of this study is to compare the effect of two drugs that can help in the prevention of regurgitation during the administration of enteral nutrition and define which one is the most effective.

Detailed description

Two prokinetic drugs (metoclopramide and erythromycin) will be compared during the administration of enteral nutrition in critically ill patients. We would like to know which one is the most effective in preventing regurgitation and risk of aspiration, which is a common complication of enteral nutritional support. This will be evaluated by measuring gastric residue every six hours.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* critically ill patients * intubated * mechanically ventilated * 18 or older age * enterally fed

Exclusion criteria

* prokinetic drugs before start study * allergy to study medication * interactions odf study medication with other drugs * recent gastro-intestinal surgery * history of esophagectomy or gastrectomy * suspicion of gastrointestinal perforation * myasthenia gravis * liver dysfunction * less than 7 days in study * gastro- or jejunostomy

Countries

Belgium

Contacts

Primary ContactNele Van De Winkel

nelevandewinkel@hotmail.com00324773348

Outcome results