Cocaine Dependence
Conditions
Keywords
Community reinforcement approach, Contingency management, 12-step facilitation counseling, Cocaine dependence, Women
Brief summary
To compare the efficacy of Community Reinforcement Approach (CRA) and 12-Step Facilitation (TSF) counseling and of voucher based reward therapy (VBRT) and a yoked, non-contingent voucher control (VC) for the treatment of cocaine dependent pregnant women or women with young children.
Detailed description
Subjects were randomly assigned to 1 of 4 treatment groups (CRA+VBRT, CRA+VC, TSF+VBRT, TSF+VC). VBRT voucher value increased for each successive cocaine-free urine sample obtained twice weekly during the 1st 12 weeks and was faded from the final earned value to $5 during the last 12 weeks. All subjects earned vouchers for attendance at scheduled twice weekly counseling sessions. Manual-guided CRA and TSF were provided by experienced clinicians.
Interventions
BEHAVIORALBehavioral therapy
Sponsors
National Institute on Drug Abuse (NIDA)
Yale University
Study design
Allocation
RANDOMIZED
Intervention model
FACTORIAL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
FEMALE
Age
18 Years to 50 Years
Healthy volunteers
No
Inclusion criteria
* Pregnant women meeting DSM IV criteria for cocaine dependence * Women meeting DSM IV criteria for cocaine dependence with custody of a young child
Exclusion criteria
* Opioid dependence * Psychosis * Severe depression * Current treatment with any anti-depressant or anti-psychotic medication * Medical instability * Inability to understand or read English
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Cocaine abstinence | 24 weeks |
Secondary
| Measure | Time frame |
|---|---|
| Reduced HIV risk behavior | 24 weeks |
Countries
United States
Outcome results
None listed