HIV Infections, Inflammation, Lipodystrophy
Conditions
Keywords
HIV, Exercise, Inflammation, Quality of life, Lipodystrophia
Brief summary
The investigators will evaluate the effects of an endurance exercise program on the physical performance, the well being, and indicators of metabolic function in patients with an HIV infection.
Interventions
BEHAVIORALExercise
12 weeks endurance training, 3 times weekly for 35 minutes
Sponsors
Charite University, Berlin, Germany
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
SUPPORTIVE_CARE
Masking
SINGLE (Investigator)
Eligibility
Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
No
Inclusion criteria
* Age 18 to 65 * HIV infection * Antiviral therapy * Understanding of written German
Exclusion criteria
* Diabetes mellitus * All conditions which can be aggravated by exercise
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Maximal oxygen uptake (VO2max) | At recruitment and after 12 weeks |
Secondary
| Measure | Time frame |
|---|---|
| Quality of life | At recruitment and after 12 weeks |
| Indicators of fat metabolism | At recruitment and after 12 weeks |
| Markers of inflammation | At recruitment and after 12 weeks |
Countries
Germany
Contacts
Primary ContactFernando Dimeo, MD
Outcome results
None listed