Study on Early Lyme Neuroborreliosis

Clinical and Microbiological Parameters in Patients With Early Lyme Neuroborreliosis

Status

UNKNOWN

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00910533

Enrollment

Registered

2009-06-01

Start date

2009-01-01

Completion date

2020-12-31

Last updated

2018-10-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Nervous System Lyme Borreliosis

Keywords

Lyme neuroborreliosis

Brief summary

The purpose of this study is to determine clinical course and the sequelae of early Lyme neuroborreliosis after treatment with ceftriaxone.

Interventions

DRUGceftriaxone

ceftriaxone 2 g od i.v. for 14 days

Study design

Allocation

NON_RANDOMIZED

Intervention model

PARALLEL

Primary purpose

OTHER

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

15 Years to No maximum

Healthy volunteers

Yes

Inclusion criteria

* erythema migrans within 4 months before neurologic involvement and pleocytosis in patients \>15 years old

Exclusion criteria

* pregnancy * lactation * history of adverse reaction to a beta-lactam antibiotic

Design outcomes

Primary

Measure	Time frame
Objective sequelae and post-treatment subjective symptoms in patients treated with ceftriaxone for early Lyme neuroborreliosis	1 year follow-up

Secondary

Measure	Time frame
Comparison of subjective symptoms between patients treated with ceftriaxone for early Lyme neuroborreliosis and control subjects without a history of Lyme borreliosis	1 year follow-up

Countries

Slovenia

Contacts

Primary ContactDasa Stupica, MD

cerar.dasa@gmail.com+38615222110

Backup ContactFranc Strle, MD

franc.strle@kclj.si+38615222110

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026