Rectal Cancer
Conditions
Keywords
Rectal cancer, Colorectal Surgery, Surgery, Local neoplasm recurrence, survival, Follow-up Study
Brief summary
Total mesorectal excision (TME) is a rather new operation technique in the treatment of rectal cancer. It is known to reduce the rate of local recurrences. However, the influence on long-term survival is unclear.
Detailed description
Background The TME technique for rectal cancer surgery was introduced in our department in summer 1995. TME is known to reduce the rate of local recurrences. However, its influence on long-term survival in unclear. All patients with rectal cancer from 1993 to 2001 are reviewed. The patients charts are reviewed and the following main characteristics are retrieved: age, gender, time of operation, operation technique, tumor stage, tumor localisation, tumor size, neoadjuvant or adjuvant treatment, complications, follow-up with respect to the appearance of local recurrences and distant metastases. Comparison of two groups of patients. Group 1: patients operated before summer 1995, that is before the introduction of TME. Group 2: patients operated after summer 1995, that is after the introduction of TME. Objective Study the influence of a new operation method (TME) on outcome (local recurrence, survival). Methods All patients with rectal cancer from 1993 to 2001 are reviewed. The patients charts are reviewed and the following main characteristics are retrieved: age, gender, time of operation, operation technique, tumor stage, tumor localisation, tumor size, neoadjuvant or adjuvant treatment, complications, follow-up with respect to the appearance of local recurrences and distant metastases. Comparison of two groups of patients. Group 1: patients operated before summer 1995, that is before the introduction of TME. Group 2: patients operated after summer 1995, that is after the introduction of TME.
Interventions
type of rectal surgery before the introduction of TME
total mesorectal excision
Sponsors
Study design
Eligibility
Inclusion criteria
* adenocarcinoma of the rectum * 16 years and older
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Local recurrence, recurrence-free survival, overall survival | 6 months and 1, 2, 3, 4 and 5 years after the operation |
Secondary
| Measure | Time frame |
|---|---|
| Surgical complications | first 30 days after the operation |
| quality of life | — |
| Percentage of patients undergoing transcatheter arterial embolisation | — |
Countries
Switzerland