Obesity, Overweight, Vitamin D Deficiency
Conditions
Keywords
Vitamin D deficiency, Adolescents, African Americans, Overweight, Obesity
Brief summary
The purpose of this study is to determine if 14-19 year old African American adolescents are able to take a daily vitamin D supplement daily for about 4 months and how well a daily dose of 400 IU or 2000 IU vitamin D supplement raises their vitamin D blood level.
Detailed description
To determine the feasibility of African American teenagers taking a daily vitamin D supplement over a 4 month period in terms of compliance and practical implementation. To determine the differences in response in blood 25-OH D level between those randomly assigned to taking a 400 IU supplement versus 2000 IU per day and to determine if there are differences in blood 25-OH D level response depending on subject gender and overweight/obese versus healthy-weight status.
Interventions
DIETARY_SUPPLEMENT2000 IU Vitamin D3 daily supplement
2000 IU vitamin D3 supplement to be taken once daily over 4 months
DIETARY_SUPPLEMENT400 IU Vitamin D3 supplement
400 IU Vitamin D3 supplement to be taken daily over 4 months
Sponsors
Augusta University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
BASIC_SCIENCE
Masking
SINGLE (Investigator)
Eligibility
Sex/Gender
ALL
Age
14 Years to 19 Years
Healthy volunteers
Yes
Inclusion criteria
* Healthy African American Adolescents
Exclusion criteria
* Hypertension * Pregnancy * Medications that affect study outcome measures * Use of other vitamin and/or mineral supplement or herbal supplements * Individuals of other races
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Plasma 25-OH D level | 3-4 months from baseline to post-testing |
Secondary
| Measure | Time frame |
|---|---|
| Blood pressure | 3-4 months from baseline to post-testing |
Countries
United States
Outcome results
None listed