Brain Tumors
Conditions
Brief summary
The purpose of this study is to get information regarding the usefulness and accuracy of this new magnetic resonance imaging (MRI) technique - termed arterial spin labeling (ASL) - in the diagnosis of pediatric brain tumors.
Detailed description
The purpose of this study is to get information regarding the usefulness and accuracy of this new MRI technique - termed arterial spin labeling (ASL) - in the diagnosis of pediatric brain tumors. This technique can non-invasively measure the blood flow to the brain during MRI examination. Because aggressive brain tumors require new blood vessels and a high level of blood supply to support its growth, we believe the tumor blood flow measured using ASL is a reliable indicator of tumor grade. This information may be useful for doctors to make treatment decisions and to monitor patients' response to treatment.
Interventions
None listed
Sponsors
Thrasher Research Fund
Children's Hospital of Philadelphia
Study design
Observational model
CASE_ONLY
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
No minimum to 18 Years
Healthy volunteers
No
Inclusion criteria
* Age 0-18 years * Primary brain tumor (newly diagnosed or recurrent) with measurable disease (at least 1cm2)
Exclusion criteria
* Patients with cardiac pacemaker or ferrous metal foreign bodies * Patients with medical problems contradictive to receiving MRI scans. * Patients requiring general anesthesia or sedation for their MRI scan. * Patients with a history of cerebrovascular disorders (stroke, moya moya) that may alter cerebral perfusion.
Countries
United States
Outcome results
None listed